Advanced Seminars in Behavioral Neuroendocrinology - Orexin/Hypocretin
Orexin Neurons Summers
Advanced Seminars in Behavioral Neuroendocrinology
Orexin/Hypocretin
Spring 2015
Orexin and receptors end
Date Speaker
streaming video
Title of the 1o Journal Paper Authors year,
journal
volume:
pages
food
Jan 16
UCL
173
Cliff Schedule and Organization CH Summers 2015 Tangi
Jan 23
UCL
173
Cliff How to chose a paper, What makes a good talk, Intinery
Guide to Seminar Design
CH Summers 2015 Tangi
Jan 30
UCL
173
Cliff Motivational activation: a unifying hypothesis of orexin/hypocretin function

Background papers: Giardino & de Lecea 14 Curr Opin Neurobiol: Hypocretin (orexin) neuromodulation of stress and reward pathways
Sakurai, 14 Nat Rev Neurosci: The role of orexin in motivated behaviours

SV Mahler
DE Moorman
RJ Smith
MH James
G Aston-Jones

2014,
Nature
Neuroscience
17:
1298–1303
Tangi
Feb 6
UCL
173
James
Robertson
GABAA receptor-mediated input change on orexin neurons following sleep deprivation in mice
Background papers:
Sakurai & Mieda, 2011 Trends Pharm Sci: Connectomics of orexin-producing neurons: interface of systems of emotion, energy homeostasis and arousal
Suzuki et al., 2013 PNAS: Behavioral and biochemical dissociation of arousal and homeostatic sleep need influenced by prior wakeful experience in mice
T Matsuki
M Takasu
Y Hirose
N Murakoshi
CM Sinton
T Motoike
M Yanagisawa
2015,
Neuroscience
284:
217–224
Justin
Feb 14
UCL
173
Zhang
Yufeng
Orexin neurons are indispensable for prostaglandin E2-induced fever and defence against environmental cooling in mice

Background papers: Sellayah and Sikder 2013 Endocrinol: Food for thought: Understanding the multifaceted nature of orexins
Zhang et al., 2010 J Physiol: Orexin neurons are indispensable for stress-induced thermogenesis in mice
Y Takahashi
W Zhang
K Sameshima
C Kuroki
A Matsumoto
J Sunanaga
Y Kono
T Sakurai
Y Kanmura
T Kuwaki
2013,
J
Physiology
591.22:
5623–5643
James
Feb 21
UCL
173
Justin
Achua
Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats

Background papers: Schoenfeld et al., 2013J NeurosciPhysical exercise prevents stress-induced activation of granule neurons and enhances local inhibitory mechanisms in the dentate gyrus
Mirescu, Peters, Gould, 2004 Nat Neurosci Early life experience alters response of adult neurogenesis to stress
MH James
EJ Campbell
FR Walker
DW Smith
HN Richardson
DM Hodgson
CV Dayas
2014
Frontiers
in Behavioral
Neuroscience
8:244:
1–9
Jayandra
February 27
UCL
190
Luke
Fuhrman
Orexin receptor-1 in the locus coeruleus plays an important role in cue-dependent fear memory consolidation

Background papers: Sears ... LeDoux, 2013PNAS Orexin/hypocretin system modulates amygdaladependent threat learning through the locus coeruleus
Ishida et al., 2002 Synapse Conditioned-Fear Stress Increases Fos Expression in Monoaminergic and GABAergic Neurons of the Locus Coeruleus and Dorsal Raphe Nuclei
KW Miyazaki
K Miyazaki
K Doya
2012
J Neurosci
32:
10451–10457
Yufeng
Apr 10
UCL
173
TJ
Agin
Binge-like consumption of ethanol and other salient reinforcers is blocked by orexin-1 receptor inhibition and leads to a reduction of hypothalamic orexin immunoreactivity

Background papers: Alcaraz-Iborra et al., 2014 Brain Behav Res Binge-like consumption of caloric and non-caloric palatable substances in ad libitum-fed C57BL/6J mice: Pharmacological and molecular evidence of orexin involvement
Cason and Aston-Jones, 2014 Neuropharmacol Role of orexin/hypocretin in conditioned sucrose-seeking in female rats
JJ Olney
M Navarro
TE Thiele
2015
Alchoholism
Clinical &
Experimental
Research
39:
21–29
Luke
May 1
UCL
173
Jayandra
Chiluwal
Hypothalamic orexin prevents hepatic insulin resistance induced by social defeat stress in mice

Background papers: Adeghate et al., 2010 PLoS ONE Orexin-1 receptor co-localizes with pancreatic hormones in Islet Cells and modulates the outcome of streptozotocin-induced diabetes mellitus
Ho et al., 2012 Physiol Behav Depressive phenotypes evoked by experimental diabetes are reversed by insulin

H Tsuneki
E Tokai
C Sugawara
T Wada
T Sakurai
T Sasaoka

2013
Neuropeptides
47:
213–219
TJ
email Orexin Take Home Messages entire group
International Society for Research on Impulsivity

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Pub Med

Use these sources to retrieve papers online

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Journals:
Amino Acids
Ann NY Acad Sci
Behav Brain Res
Behav Neurosci
Brain Res Bull
Cerebral Cortex
Endocrinol
Hormones and Behavior
Euro J Neurosci
J Comp Neurol
J Neurosci
J Physiol
Nature Cell Biol
Neurobiol Disease
Neuron
Neuropharmacol
Neuroscience
Phil Trans R Soc B
PLoS ONE
Psychopharmacol
Stem Cells and Development

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